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chlorambucil

Term Information

Accession
CHEBI:28830
Name
chlorambucil
Ontology
Synonyms
4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid, CHLORAMBUCIL, Chlorambucil, 4-(p-bis(beta-chloroethyl)aminophenyl)butyric acid, 4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acid, Ambochlorin, Leukeran, N,N-di-2-chloroethyl-gamma-p-aminophenylbutyric acid, chloraminophen, gamma-[p-di(2-chloroethyl)aminophenyl]butyric acid, phenylbutyric acid nitrogen mustard
Alternate IDs
None
Definition
A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia. [source: unknown]
Comment
None
Subset
None
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Graph of CHEBI:28830

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Parents of chlorambucil (CHEBI:28830)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
chlorambucil [is_a relation] is_a  tertiary amino compound (CHEBI:50996)
chlorambucil [is_a relation] is_a  monocarboxylic acid (CHEBI:25384)
chlorambucil [is_a relation] is_a  organochlorine compound (CHEBI:36683)
chlorambucil [RO:0000087 relation] RO:0000087  immunosuppressive agent (CHEBI:35705)
chlorambucil [RO:0000087 relation] RO:0000087  alkylating agent (CHEBI:22333)
chlorambucil [RO:0000087 relation] RO:0000087  antineoplastic agent (CHEBI:35610)
chlorambucil [is_a relation] is_a  nitrogen mustard (CHEBI:37598)
chlorambucil [RO:0000087 relation] RO:0000087  drug allergen (CHEBI:88188)
chlorambucil [RO:0000087 relation] RO:0000087  carcinogenic agent (CHEBI:50903)
chlorambucil [is_a relation] is_a  aromatic amine (CHEBI:33860)

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