Planteome: Term Details for "EC 5.99.1.2 (DNA topoisomerase) inhibitor" (CHEBI:50276)

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Term Information

Accession: CHEBI:50276
Name: EC 5.99.1.2 (DNA topoisomerase) inhibitor
Ontology
Synonyms: DNA topoisomerase inhibitor, DNA topoisomerase inhibitors, EC 5.99.1.2 (DNA topoisomerase) inhibitors, EC 5.99.1.2 (topoisomerase I) inhibitor, EC 5.99.1.2 (topoisomerase I) inhibitors, EC 5.99.1.2 inhibitor, EC 5.99.1.2 inhibitors, topoisomerase I (EC 5.99.1.2) inhibitor, topoisomerase I (EC 5.99.1.2) inhibitors, topoisomerase I inhibitor, topoisomerase I inhibitors, type I DNA topoisomerase inhibitor, type I DNA topoisomerase inhibitors
Alternate IDs: None
Definition: A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA. [source: unknown]
Comment: None
Subset: None
Related: Link to all annotated objects annotated to EC 5.99.1.2 (DNA topoisomerase) inhibitor.; Link to all direct and indirect annotations to EC 5.99.1.2 (DNA topoisomerase) inhibitor.; Link to all direct and indirect annotations download (limited to first 10,000) for EC 5.99.1.2 (DNA topoisomerase) inhibitor.
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