Planteome: Term Details for "SAGA complex" (GO:0000124)

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Term Information

Accession: GO:0000124
Name: SAGA complex
Ontology: cellular_component
Synonyms: Spt-Ada-Gcn5-acetyltransferase complex, SPT3-TAF9-GCN5 acetylase complex, STAGA coactivator complex, STAGA complex, PCAF complex, PCAF histone acetylase-associated complex, SPT3-TAF9-PCAF acetylase complex
Alternate IDs: GO:0000125, GO:0030914
Definition: A SAGA-type histone acetyltransferase complex that deubiquitinates H2A and/or H2B. This complex is organized into several functional submodules: a structural core including the activator binding module and consisting of ADA1 or a homolog, members of the SPT and TAF protein families as well as promotor recruitment factor TRRAP/TRA1, a histone acetyltransferase (HAT) module consisting of GCN5/KAT2A or PCAF/KAT2B, ADA2, ADA3/NGG1, and SGF29 or homologues thereof, a histone deubiquitinase (DUB) module consisting of ATXN7/SGF73, ATXN7L3/SGF11, ENY2/SUS1 and USP22/UBP8 or homologues thereof, and in some taxa a splicing module consisting of SF3B3 and SF3B5 or homologues thereof (not in fungi). In budding yeast also contains Spt8 which distinguishes it from SAGA-like (SLIK) complex (GO:0046695). Source: PMID:19056896, PMID:33004486, PMID:17337012, PMID:20838651, PMID:10637607
Comment: None
History: See term history for GO:0000124 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to SAGA complex.; Link to all direct and indirect annotations to SAGA complex.; Link to all direct and indirect annotations download (limited to first 10,000) for SAGA complex.
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