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Group I intron splicing
Term Information
Accession
GO:0000372
Name
Group I intron splicing
Ontology
biological_process
Synonyms
mRNA splicing
Alternate IDs
None
Definition
The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize).
Source:
GOC:krc,
PMID:11377794
Comment
Note that Group I introns are known to be found in a number of places: rRNA, mRNA, and tRNA in organelles of fungi, plants, and protists; tRNA and mRNA of bacteria and bacteriophage; rRNA of protists and fungi; and occasionally in mRNA of animal mitochondria (e.g. sea anemone).
Link
to all annotated objects annotated to Group I intron splicing.
Link
to all direct and indirect annotations
to Group I intron splicing.
Link
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for Group I intron splicing.
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