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antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

Term Information

Accession
GO:0002479
Name
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
Ontology
biological_process
Synonyms
TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent exogenous peptide antigen processing and presentation via MHC class I, exogenous peptide antigen processing and presentation via MHC class I, TAP-dependent, cross presentation, cross-presentation
Alternate IDs
None
Definition
The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules. Source: PMID:15224093, GOC:add, PMID:15771591, PMID:16181335
Comment
None
History
See term history for GO:0002479 at QuickGO
Subset
None
Feedback
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Parents of antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:0002479)
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antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [is_a relation] is_a  antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)

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