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Term Information

Accession
GO:0002753
Name
cytosolic pattern recognition receptor signaling pathway
Ontology
biological_process
Synonyms
cytoplasmic PAMP receptor signaling pathway, cytoplasmic PRR signaling pathway, cytoplasmic pathogen receptor signaling pathway, cytoplasmic pattern recognition receptor signaling pathway, cytoplasmic pattern recognition receptor signalling pathway, cytoplasmic caspase-recruiting domain (CARD) helicase signaling pathway, cytoplasmic pattern recognition receptor signaling pathway in response to virus, cytoplasmic pattern recognition receptor signalling pathway in response to virus, virus-induced cytoplasmic pattern recognition receptor signaling pathway
Alternate IDs
GO:0039528
Definition
The series of molecular signals initiated by the binding of a ligand from another organism to a cytosolic pattern recognition receptor (PRR). PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species. Source: PMID:21187438, PMID:15199967, PMID:18272355, ISBN:0781735149, GOC:ar, GOC:add, PMID:19531363, PMID:17328678
Comment
This term should be used for annotation when it is not known which cytoplasmic pattern recognition receptor (PRR) has been activated. If the PRR is known, consider instead the child terms. The RIG-like family is composed of at least RIG-I (retinoic acid inducible gene I; also known as DDX58), melanoma differentiation-associated gene 5 (MDA5; also known as helicard or IFIH1) and LGP2.
History
See term history for GO:0002753 at QuickGO
Subset
None
Feedback
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Graph of GO:0002753

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Parents of cytosolic pattern recognition receptor signaling pathway (GO:0002753)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cytosolic pattern recognition receptor signaling pathway [is_a relation] is_a  intracellular receptor signaling pathway (GO:0030522)
cytosolic pattern recognition receptor signaling pathway [is_a relation] is_a  pattern recognition receptor signaling pathway (GO:0002221)
cytosolic pattern recognition receptor signaling pathway [BFO:0000051 relation] BFO:0000051  positive regulation of cytokine production (GO:0001819)
Children of cytosolic pattern recognition receptor signaling pathway (GO:0002753)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nucleotide-binding oligomerization domain containing signaling pathway (GO:0070423) [is_a relation] is_a  cytosolic pattern recognition receptor signaling pathway
endosomal pattern recognition receptor signaling pathway (GO:0002754) [is_a relation] is_a  cytosolic pattern recognition receptor signaling pathway
MDA-5 signaling pathway (GO:0039530) [is_a relation] is_a  cytosolic pattern recognition receptor signaling pathway
RIG-I signaling pathway (GO:0039529) [is_a relation] is_a  cytosolic pattern recognition receptor signaling pathway
cGAS/STING signaling pathway (GO:0140896) [is_a relation] is_a  cytosolic pattern recognition receptor signaling pathway
negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039532) [RO:0002212 relation] RO:0002212  cytosolic pattern recognition receptor signaling pathway
regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) [RO:0002211 relation] RO:0002211  cytosolic pattern recognition receptor signaling pathway
endolysosomal toll-like receptor signaling pathway (GO:0140894) [is_a relation] is_a  cytosolic pattern recognition receptor signaling pathway
None.