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Term Information

Accession
GO:0002937
Name
tRNA 4-thiouridine biosynthesis
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The processes whereby a uridine residue in a tRNA is converted to 4-thiouridine. Typically 4-thiouridine is found at position 8, in many transfer RNAs. Source: ISBN:155581073X
Comment
In E. coli, two genes are involved, nuvA (aka Thi) and NuvC (aka iscS) . NuvA converts the trNA into an unidentified intermediate in an ATP dependent manner. NucC catalyzes the second step, transferring the sulfur from cysteine to an unidentified intermediate. NuvC also participates in thiamine synthesis.
History
See term history for GO:0002937 at QuickGO
Subset
None
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Graph of GO:0002937

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Parents of tRNA 4-thiouridine biosynthesis (GO:0002937)
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tRNA 4-thiouridine biosynthesis [is_a relation] is_a  tRNA thio-modification (GO:0034227)

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