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leukotriene-C(4) hydrolase
Term Information
Accession
GO:0002951
Name
leukotriene-C(4) hydrolase
Ontology
molecular_function
Synonyms
None
Alternate IDs
None
Definition
Catalysis of the reaction leukotriene C(4) + H2O= leukotriene D(4) + L-glutamate.
Source:RHEA:31563,
PMID:9774450
Comment
The mouse enzyme is specific for leukotriene C(4), while the human enzyme also has considerable activity toward glutathione and oxidized glutathione (cf. EC:3.4.19.13). PMID:9774450 cites that the mouse form of this enzyme failed to measure activity towards glutathione.
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