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Term Information

Accession
GO:0004108
Name
citrate (Si)-synthase activity
Ontology
molecular_function
Synonyms
(R)-citric synthase activity, acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming], citrate condensing enzyme activity, citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)->acetyl-CoA) activity, citrate oxaloacetate-lyase ((pro-3S)-CH2COO-rightacetyl-CoA), citrate oxaloacetate-lyase [(pro-3S)-CH2COOrightacetyl-CoA], citrate oxaloacetate-lyase, CoA-acetylating activity, citrate synthetase activity, citric synthase activity, citric-condensing enzyme activity, citrogenase activity, oxalacetic transacetase activity, oxaloacetate transacetase activity, citrate synthase activity, condensing enzyme activity
Alternate IDs
None
Definition
Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group. Source: EC:2.3.3.1
Comment
Note that this function was formerly EC:4.1.3.7.
History
See term history for GO:0004108 at QuickGO
Subset
None
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Parents of citrate (Si)-synthase activity (GO:0004108)
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citrate (Si)-synthase activity [is_a relation] is_a  citrate synthase activity (GO:0036440)

This term has no children.

EC
2.3.3.1
MetaCyc
CITSYN-RXN
Reactome
R-HSA-70975