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Term Information

Accession
GO:0004518
Name
nuclease activity
Ontology
molecular_function
Synonyms
None
Alternate IDs
None
Definition
Catalysis of the hydrolysis of ester linkages within nucleic acids. Source: ISBN:0198547684
Comment
Note that 'tRNA nucleotidyltransferase activity ; GO:0009022', also known as 'ribonuclease PH', and 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906' do not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis.
History
See term history for GO:0004518 at QuickGO
Subset
goslim_drosophila
goslim_chembl
goslim_generic
goslim_plant
goslim_yeast
Feedback
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Graph of GO:0004518

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Parents of nuclease activity (GO:0004518)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nuclease activity [is_a relation] is_a  hydrolase activity, acting on ester bonds (GO:0016788)
nuclease activity [BFO:0000050 relation] BFO:0000050  nucleic acid phosphodiester bond hydrolysis (GO:0090305)
Children of nuclease activity (GO:0004518)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of nuclease activity (GO:0032075) [RO:0002213 relation] RO:0002213  nuclease activity
negative regulation of nuclease activity (GO:0032074) [RO:0002212 relation] RO:0002212  nuclease activity
regulation of nuclease activity (GO:0032069) [RO:0002211 relation] RO:0002211  nuclease activity
deoxyribonuclease activity (GO:0004536) [is_a relation] is_a  nuclease activity
endonuclease activity (GO:0004519) [is_a relation] is_a  nuclease activity
ribonuclease activity (GO:0004540) [is_a relation] is_a  nuclease activity
exonuclease activity (GO:0004527) [is_a relation] is_a  nuclease activity
oligonucleotidase activity (GO:0008946) [is_a relation] is_a  nuclease activity
None.