Planteome: Term Details for "protein-arginine deiminase activity" (GO:0004668)

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Term Information

Accession: GO:0004668
Name: protein-arginine deiminase activity
Ontology: molecular_function
Synonyms: peptidylarginine deiminase activity, protein-L-arginine iminohydrolase activity
Alternate IDs: None
Definition: Catalysis of the reaction: H2O + L-arginyl-[protein] = L-citrullyl-[protein] + NH4+, resulting in citrullination of the target protein. This reaction is calcium-dependent. Source: PMID:27393304
Comment: None
History: See term history for GO:0004668 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to protein-arginine deiminase activity.; Link to all direct and indirect annotations to protein-arginine deiminase activity.; Link to all direct and indirect annotations download (limited to first 10,000) for protein-arginine deiminase activity.
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BFO:0000001 entity
BFO:0000003 occurrent
BFO:0000015 process
GO:0008150 biological_process
GO:0008152 metabolic process
GO:0003674 molecular_function
GO:0006807 nitrogen compound metabolic process
GO:0071704 organic substance metabolic process
GO:0003824 catalytic activity
GO:0043170 macromolecule metabolic process
GO:1901564 organonitrogen compound metabolic process
GO:0044238 primary metabolic process
GO:0016787 hydrolase activity
GO:0043412 macromolecule modification
GO:0019538 protein metabolic process
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0036211 protein modification process
GO:0016570 histone modification
GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
GO:0004668 protein-arginine deiminase activity
GO:0140794 histone arginine deiminase activity

Parents of protein-arginine deiminase activity (GO:0004668)

subject	relation	object
protein-arginine deiminase activity	BFO:0000050	histone modification (GO:0016570)
protein-arginine deiminase activity	is_a	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines (GO:0016813)

Children of protein-arginine deiminase activity (GO:0004668)

subject	relation	object
histone arginine deiminase activity (GO:0140794)	is_a	protein-arginine deiminase activity

EC: 3.5.3.15
MetaCyc: PROTEIN-ARGININE-DEIMINASE-RXN
Reactome: R-HSA-3247569; R-HSA-1183128
RHEA: 18089