Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains.
Source:
GOC:krc,
GOC:cilia,
GOC:hla,
PMID:12600311,
GOC:mah
Comment
Note that this term is labelled based on phylogenetic classification and community usage, rather than strict cellular localization. Cytoplasmic dynein complexes may contain ciliary dyneins; therefore the term is not linked to 'cytoplasm'. Cytoplasmic dynein complexes do not contain axonemal dyneins; see GO:0005858 axonemal dynein complex.
Link
to all annotated objects annotated to cytoplasmic dynein complex.
Link
to all direct and indirect annotations
to cytoplasmic dynein complex.
Link
to all direct and indirect annotations download (limited to first 10,000)
for cytoplasmic dynein complex.
Feedback
Contact the
Planteome feedback
if you find mistakes or have concerns
about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.