Planteome: Term Details for "complement activation" (GO:0006956)

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Term Information

Accession: GO:0006956
Name: complement activation
Ontology: biological_process
Synonyms: complement cascade, complement response, complement activity
Alternate IDs: None
Definition: Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway. Source: ISBN:0781735149, GOC:add, GO_REF:0000022
Comment: None
History: See term history for GO:0006956 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to complement activation.; Link to all direct and indirect annotations to complement activation.; Link to all direct and indirect annotations download (limited to first 10,000) for complement activation.
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GO:0008150 biological_process
GO:0065007 biological regulation
BFO:0000001 entity
GO:0002376 immune system process
BFO:0000003 occurrent
GO:0050789 regulation of biological process
GO:0050896 response to stimulus
GO:0006955 immune response
GO:0048518 positive regulation of biological process
BFO:0000015 process
GO:0002682 regulation of immune system process
GO:0048583 regulation of response to stimulus
GO:0002684 positive regulation of immune system process
GO:0048584 positive regulation of response to stimulus
GO:0050776 regulation of immune response
GO:0050778 positive regulation of immune response
GO:0002253 activation of immune response
GO:0006959 humoral immune response
GO:0002252 immune effector process
GO:0006956 complement activation
GO:0001905 activation of membrane attack complex
GO:0006957 complement activation, alternative pathway
GO:0006958 complement activation, classical pathway
GO:0001867 complement activation, lectin pathway
GO:0045916 negative regulation of complement activation
GO:0045917 positive regulation of complement activation
GO:0030449 regulation of complement activation

Parents of complement activation (GO:0006956)

subject	relation	object
complement activation	BFO:0000051	protein activation cascade (GO:0072376)
complement activation	is_a	immune effector process (GO:0002252)
complement activation	is_a	humoral immune response (GO:0006959)
complement activation	is_a	activation of immune response (GO:0002253)

Children of complement activation (GO:0006956)

subject	relation	object
activation of membrane attack complex (GO:0001905)	is_a	complement activation
complement activation, classical pathway (GO:0006958)	is_a	complement activation
positive regulation of complement activation (GO:0045917)	RO:0002213	complement activation
complement activation, alternative pathway (GO:0006957)	is_a	complement activation
complement activation, lectin pathway (GO:0001867)	is_a	complement activation
negative regulation of complement activation (GO:0045916)	RO:0002212	complement activation
regulation of complement activation (GO:0030449)	RO:0002211	complement activation
complement-dependent cytotoxicity (GO:0097278)	BFO:0000051	complement activation