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Term Information

Accession
GO:0007227
Name
signal transduction downstream of smoothened
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The series of molecular signals that are initiated by the transmembrane protein Smoothened. In the presence of a Hedgehog signaling molecule, the Patched protein no longer inhibits the activity of Smoothened, and Smoothened signals via the Hedgehog signaling complex to activate downstream components of the Hedgehog signaling pathway. Source: PMID:15057936
Comment
None
History
See term history for GO:0007227 at QuickGO
Subset
None
Feedback
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Graph of GO:0007227

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Parents of signal transduction downstream of smoothened (GO:0007227)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
signal transduction downstream of smoothened [is_a relation] is_a  intracellular signal transduction (GO:0035556)
signal transduction downstream of smoothened [BFO:0000050 relation] BFO:0000050  smoothened signaling pathway (GO:0007224)
Children of signal transduction downstream of smoothened (GO:0007227)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of hh target transcription factor activity (GO:0007228) [BFO:0000050 relation] BFO:0000050  signal transduction downstream of smoothened
None.