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metallopeptidase activity

Term Information

Accession
GO:0008237
Name
metallopeptidase activity
Ontology
molecular_function
Synonyms
metalloprotease activity, metalloproteinase activity
Alternate IDs
None
Definition
Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. Source: https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE, GOC:mah
Comment
None
History
See term history for GO:0008237 at QuickGO
Subset
None
Feedback
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Graph of GO:0008237

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Parents of metallopeptidase activity (GO:0008237)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
metallopeptidase activity [is_a relation] is_a  peptidase activity (GO:0008233)
Children of metallopeptidase activity (GO:0008237)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
metalloendopeptidase activity (GO:0004222) [is_a relation] is_a  metallopeptidase activity
regulation of metallopeptidase activity (GO:1905048) [RO:0002211 relation] RO:0002211  metallopeptidase activity
metalloexopeptidase activity (GO:0008235) [is_a relation] is_a  metallopeptidase activity
metal-dependent deubiquitinase activity (GO:0140492) [is_a relation] is_a  metallopeptidase activity
positive regulation of metallopeptidase activity (GO:1905050) [RO:0002213 relation] RO:0002213  metallopeptidase activity
metal-dependent deNEDDylase activity (GO:0140758) [is_a relation] is_a  metallopeptidase activity
negative regulation of metallopeptidase activity (GO:1905049) [RO:0002212 relation] RO:0002212  metallopeptidase activity