Planteome: Term Details for "RNA interference" (GO:0016246)

You are using the Cyverse mirror of the Planteome Ontology Browser. The main site is at browser.planteome.org.

Notice

Some functionality on this page depends on JavaScript. To fully use the features of AmiGO 2, enable JavaScript in your browser and reload from the landing page.

Term Information

Accession: GO:0016246
Name: RNA interference
Ontology: biological_process
Synonyms: RNAi, posttranscriptional gene silencing by siRNA
Alternate IDs: None
Definition: The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes. Source: GOC:ems, PMID:11713190, PMID:11201747, PMID:18771919
Comment: Note that this term refers specifically to posttranscriptional mechanisms by which small interfering RNAs down-regulate gene expression. Also consider annotating to other descendants of 'gene silencing by RNA ; GO:0031047'.
History: See term history for GO:0016246 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to RNA interference.; Link to all direct and indirect annotations to RNA interference.; Link to all direct and indirect annotations download (limited to first 10,000) for RNA interference.
Feedback: Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

External term view.

Viewing options

GO:0008150 biological_process
GO:0065007 biological regulation
BFO:0000001 entity
GO:0008152 metabolic process
GO:0050789 regulation of biological process
GO:0048519 negative regulation of biological process
BFO:0000003 occurrent
GO:0071704 organic substance metabolic process
GO:0019222 regulation of metabolic process
GO:0043170 macromolecule metabolic process
GO:0009892 negative regulation of metabolic process
BFO:0000015 process
GO:0060255 regulation of macromolecule metabolic process
GO:0010467 gene expression
GO:0010605 negative regulation of macromolecule metabolic process
GO:0010468 regulation of gene expression
GO:0009987 cellular process
GO:0010629 negative regulation of gene expression
GO:0016458 gene silencing
GO:0010608 posttranscriptional regulation of gene expression
GO:0031047 gene silencing by RNA
GO:0016441 posttranscriptional gene silencing
GO:0035194 post-transcriptional gene silencing by RNA
GO:0016246 RNA interference
GO:0090625 mRNA cleavage involved in gene silencing by siRNA
GO:1900369 negative regulation of RNA interference
GO:0070549 negative regulation of translation involved in RNA interference
GO:1900370 positive regulation of RNA interference
GO:0010599 production of lsiRNA involved in RNA interference
GO:0030422 production of siRNA involved in RNA interference
GO:1900368 regulation of RNA interference
GO:1903453 RNA interference involved in olfactory learning
GO:0035087 siRNA loading onto RISC involved in RNA interference
GO:0030423 targeting of mRNA for destruction involved in RNA interference
GO:0036453 transitive RNA interference

Parents of RNA interference (GO:0016246)

subject	relation	object
RNA interference	is_a	post-transcriptional gene silencing by RNA (GO:0035194)

Children of RNA interference (GO:0016246)

subject	relation	object
mRNA cleavage involved in gene silencing by siRNA (GO:0090625)	BFO:0000050	RNA interference
positive regulation of RNA interference (GO:1900370)	RO:0002213	RNA interference
targeting of mRNA for destruction involved in RNA interference (GO:0030423)	BFO:0000050	RNA interference
production of lsiRNA involved in RNA interference (GO:0010599)	BFO:0000050	RNA interference
production of siRNA involved in RNA interference (GO:0030422)	BFO:0000050	RNA interference
regulation of RNA interference (GO:1900368)	RO:0002211	RNA interference
negative regulation of translation involved in RNA interference (GO:0070549)	BFO:0000050	RNA interference
siRNA loading onto RISC involved in RNA interference (GO:0035087)	BFO:0000050	RNA interference
transitive RNA interference (GO:0036453)	is_a	RNA interference
negative regulation of RNA interference (GO:1900369)	RO:0002212	RNA interference
RNA interference involved in olfactory learning (GO:1903453)	is_a	RNA interference

Wikipedia: RNA_interference