Planteome: Term Details for "mediator complex" (GO:0016592)

You are using the Cyverse mirror of the Planteome Ontology Browser. The main site is at browser.planteome.org.

Notice

Some functionality on this page depends on JavaScript. To fully use the features of AmiGO 2, enable JavaScript in your browser and reload from the landing page.

Term Information

Accession: GO:0016592
Name: mediator complex
Ontology: cellular_component
Synonyms: L mediator complex, Srb-mediator complex, CDK8-containing TRAP/mediator complex, TRAP complex
Alternate IDs: GO:0000119
Definition: A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The mediator complex is required for activation of transcription of most protein-coding genes, but can also act as a transcriptional corepressor. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins. Source: PMID:16168358, PMID:11454195, PMID:17870225
Comment: None
History: See term history for GO:0016592 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to mediator complex.; Link to all direct and indirect annotations to mediator complex.; Link to all direct and indirect annotations download (limited to first 10,000) for mediator complex.
Feedback: Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

External term view.

Viewing options

GO:0005575 cellular_component
GO:0110165 cellular anatomical entity
GO:0005622 intracellular anatomical structure
GO:0043226 organelle
GO:0043229 intracellular organelle
GO:0043227 membrane-bounded organelle
GO:0043231 intracellular membrane-bounded organelle
GO:0005634 nucleus
GO:0032991 protein-containing complex
GO:0140513 nuclear protein-containing complex
GO:0016592 mediator complex

Parents of mediator complex (GO:0016592)

subject	relation	object
mediator complex	BFO:0000051	core mediator complex (GO:0070847)
mediator complex	is_a	nuclear protein-containing complex (GO:0140513)

This term has no children.

Wikipedia: Mediator_(coactivator)