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mitotic checkpoint complex

Term Information

Accession
GO:0033597
Name
mitotic checkpoint complex
Ontology
cellular_component
Synonyms
MCC
Alternate IDs
None
Definition
A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20. Source: PMID:11726501, PMID:17650307, PMID:10704439, PMID:11535616
Comment
None
History
See term history for GO:0033597 at QuickGO
Subset
None
Feedback
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Graph of GO:0033597

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Parents of mitotic checkpoint complex (GO:0033597)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
mitotic checkpoint complex [BFO:0000051 relation] BFO:0000051  bub1-bub3 complex (GO:1990298)
mitotic checkpoint complex [is_a relation] is_a  nuclear protein-containing complex (GO:0140513)
Children of mitotic checkpoint complex (GO:0033597)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
mitotic checkpoint complex, CDC20-MAD2 subcomplex (GO:1990333) [BFO:0000050 relation] BFO:0000050  mitotic checkpoint complex
None.