Planteome: Term Details for "PRC1 complex" (GO:0035102)

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Term Information

Accession: GO:0035102
Name: PRC1 complex
Ontology: cellular_component
Synonyms: Polycomb repressive complex 1
Alternate IDs: None
Definition: A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling. Source: GOC:bf, PMID:10412979
Comment: In Drosophila the core subunits are Pc (Polycomb), Psc (Posterior sex combs), Ph (Polyhomeotic) and Sce (Sex comb extra). In mammals, which have several orthologs for each of the Drosophila core proteins, a family of distinct PRC1-like complexes seem to exist which contain at least some PcG proteins in mutually exclusive manner.
History: See term history for GO:0035102 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to PRC1 complex.; Link to all direct and indirect annotations to PRC1 complex.; Link to all direct and indirect annotations download (limited to first 10,000) for PRC1 complex.
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