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Term Information

Accession
GO:0035103
Name
sterol regulatory element binding protein cleavage
Ontology
biological_process
Synonyms
SREBP cleavage, sterol depletion response, SREBP cleavage, sterol regulatory element binding protein cleavage involved in ER-nuclear sterol response pathway
Alternate IDs
GO:0006992
Definition
The proteolytic release of a transcriptionally active sterol regulatory element binding protein (SREBP) from intracellular membranes, freeing it to move to the nucleus to upregulate transcription of target genes, in response to altered levels of one or more lipids. Source: PMID:12923525, GOC:vw, GOC:bf
Comment
None
History
See term history for GO:0035103 at QuickGO
Subset
None
Feedback
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Graph of GO:0035103

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Parents of sterol regulatory element binding protein cleavage (GO:0035103)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
sterol regulatory element binding protein cleavage [is_a relation] is_a  cellular protein metabolic process (GO:0044267)
sterol regulatory element binding protein cleavage [is_a relation] is_a  protein processing (GO:0016485)
sterol regulatory element binding protein cleavage [BFO:0000050 relation] BFO:0000050  SREBP signaling pathway (GO:0032933)
Children of sterol regulatory element binding protein cleavage (GO:0035103)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of sterol regulatory element binding protein cleavage (GO:1901310) [RO:0002213 relation] RO:0002213  sterol regulatory element binding protein cleavage
negative regulation of sterol regulatory element binding protein cleavage (GO:1901309) [RO:0002212 relation] RO:0002212  sterol regulatory element binding protein cleavage
regulation of sterol regulatory element binding protein cleavage (GO:1901308) [RO:0002211 relation] RO:0002211  sterol regulatory element binding protein cleavage
None.