Planteome: Term Details for "gene silencing by miRNA" (GO:0035195)

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Term Information

Accession: GO:0035195
Name: gene silencing by miRNA
Ontology: biological_process
Synonyms: gene silencing by microRNA, miRNA-mediated gene silencing, microRNA-mediated gene silencing
Alternate IDs: None
Definition: Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endolytic cleavage of the RNA (often mRNA) or mRNA translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA. Source: PMID:28379604, PMID:23985560, GOC:bc, PMID:15066283, PMID:14744438, GOC:aruk, PMID:15066275, GOC:rl, PMID:23209154
Comment: None
History: See term history for GO:0035195 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to gene silencing by miRNA.; Link to all direct and indirect annotations to gene silencing by miRNA.; Link to all direct and indirect annotations download (limited to first 10,000) for gene silencing by miRNA.
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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GO:0008150 biological_process
GO:0065007 biological regulation
BFO:0000001 entity
GO:0008152 metabolic process
GO:0050789 regulation of biological process
GO:0048519 negative regulation of biological process
BFO:0000003 occurrent
GO:0071704 organic substance metabolic process
GO:0019222 regulation of metabolic process
GO:0043170 macromolecule metabolic process
GO:0009892 negative regulation of metabolic process
BFO:0000015 process
GO:0060255 regulation of macromolecule metabolic process
GO:0010467 gene expression
GO:0010605 negative regulation of macromolecule metabolic process
GO:0010468 regulation of gene expression
GO:0009987 cellular process
GO:0010629 negative regulation of gene expression
GO:0016458 gene silencing
GO:0010608 posttranscriptional regulation of gene expression
GO:0031047 gene silencing by RNA
GO:0016441 posttranscriptional gene silencing
GO:0035194 post-transcriptional gene silencing by RNA
GO:0035195 gene silencing by miRNA
GO:0098806 deadenylation involved in gene silencing by miRNA
GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA
GO:0035278 miRNA mediated inhibition of translation
GO:0035279 mRNA cleavage involved in gene silencing by miRNA
GO:0060965 negative regulation of gene silencing by miRNA
GO:2000637 positive regulation of gene silencing by miRNA
GO:0035281 pre-miRNA export from nucleus
GO:0035196 production of miRNAs involved in gene silencing by miRNA
GO:0060964 regulation of gene silencing by miRNA

Parents of gene silencing by miRNA (GO:0035195)

subject	relation	object
gene silencing by miRNA	is_a	post-transcriptional gene silencing by RNA (GO:0035194)

Children of gene silencing by miRNA (GO:0035195)

subject	relation	object
deadenylation involved in gene silencing by miRNA (GO:0098806)	BFO:0000050	gene silencing by miRNA
regulation of gene silencing by miRNA (GO:0060964)	RO:0002211	gene silencing by miRNA
negative regulation of gene silencing by miRNA (GO:0060965)	RO:0002212	gene silencing by miRNA
miRNA loading onto RISC involved in gene silencing by miRNA (GO:0035280)	BFO:0000050	gene silencing by miRNA
miRNA mediated inhibition of translation (GO:0035278)	BFO:0000050	gene silencing by miRNA
pre-miRNA export from nucleus (GO:0035281)	BFO:0000050	gene silencing by miRNA
production of miRNAs involved in gene silencing by miRNA (GO:0035196)	BFO:0000050	gene silencing by miRNA
positive regulation of gene silencing by miRNA (GO:2000637)	RO:0002213	gene silencing by miRNA
mRNA cleavage involved in gene silencing by miRNA (GO:0035279)	BFO:0000050	gene silencing by miRNA