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Term Information

Accession
GO:0035243
Name
protein-arginine omega-N symmetric methyltransferase activity
Ontology
molecular_function
Synonyms
protein arginine omega-N symmetric methylase activity, protein arginine omega-N symmetric methyltransferase activity, S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega,Nomega'-dimethyl-L-arginine-forming), type II PRMT activity, type II protein arginine methyltransferase activity
Alternate IDs
None
Definition
Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues. Source: EC:2.1.1.320, PMID:14705965, RESID:AA0067, RESID:AA0069
Comment
Note that type II protein arginine N-methyltransferase enzymes possess 'protein-arginine omega-N monomethyltransferase activity ; GO:0035241' and 'protein-arginine omega-N symmetric methyltransferase activity ; GO:0035243'.
History
See term history for GO:0035243 at QuickGO
Subset
None
Feedback
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Graph of GO:0035243

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Parents of protein-arginine omega-N symmetric methyltransferase activity (GO:0035243)
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protein-arginine omega-N symmetric methyltransferase activity [is_a relation] is_a  protein-arginine N-methyltransferase activity (GO:0016274)

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EC
2.1.1.320
Reactome
R-HSA-6804383
RESID
AA0067
AA0069
RHEA
48108