Planteome: Term Details for "mRNA cleavage involved in gene silencing by miRNA" (GO:0035279)

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Term Information

Accession: GO:0035279
Name: mRNA cleavage involved in gene silencing by miRNA
Ontology: biological_process
Synonyms: gene silencing by miRNA, mRNA cleavage, mRNA cleavage involved in gene silencing by microRNA, miRNA-mediated gene silencing, mRNA cleavage
Alternate IDs: None
Definition: The process in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism. Source: GOC:dph, PMID:15196554, GOC:mtg_lung, PMID:14744438
Comment: None
History: See term history for GO:0035279 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to mRNA cleavage involved in gene silencing by miRNA.; Link to all direct and indirect annotations to mRNA cleavage involved in gene silencing by miRNA.; Link to all direct and indirect annotations download (limited to first 10,000) for mRNA cleavage involved in gene silencing by miRNA.
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GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0065007 biological regulation
GO:0044237 cellular metabolic process
GO:0006807 nitrogen compound metabolic process
GO:0071704 organic substance metabolic process
GO:0006725 cellular aromatic compound metabolic process
GO:0034641 cellular nitrogen compound metabolic process
BFO:0000001 entity
GO:0046483 heterocycle metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:0044238 primary metabolic process
GO:0050789 regulation of biological process
GO:0043170 macromolecule metabolic process
GO:0048519 negative regulation of biological process
GO:0006139 nucleobase-containing compound metabolic process
BFO:0000003 occurrent
GO:0019222 regulation of metabolic process
GO:0010467 gene expression
GO:0009892 negative regulation of metabolic process
GO:0090304 nucleic acid metabolic process
BFO:0000015 process
GO:0010468 regulation of gene expression
GO:0060255 regulation of macromolecule metabolic process
GO:0016458 gene silencing
GO:0010605 negative regulation of macromolecule metabolic process
GO:0090305 nucleic acid phosphodiester bond hydrolysis
GO:0010608 posttranscriptional regulation of gene expression
GO:0016070 RNA metabolic process
GO:0031047 gene silencing by RNA
GO:0016071 mRNA metabolic process
GO:0010629 negative regulation of gene expression
GO:0016441 posttranscriptional gene silencing
GO:0090501 RNA phosphodiester bond hydrolysis
GO:0006379 mRNA cleavage
GO:0035194 post-transcriptional gene silencing by RNA
GO:0035195 gene silencing by miRNA
GO:0098795 mRNA cleavage involved in gene silencing
GO:0035279 mRNA cleavage involved in gene silencing by miRNA
GO:0090624 endoribonuclease activity, cleaving miRNA-paired mRNA

Parents of mRNA cleavage involved in gene silencing by miRNA (GO:0035279)

subject	relation	object
mRNA cleavage involved in gene silencing by miRNA	BFO:0000050	gene silencing by miRNA (GO:0035195)
mRNA cleavage involved in gene silencing by miRNA	is_a	mRNA cleavage involved in gene silencing (GO:0098795)

Children of mRNA cleavage involved in gene silencing by miRNA (GO:0035279)

subject	relation	object
endoribonuclease activity, cleaving miRNA-paired mRNA (GO:0090624)	BFO:0000050	mRNA cleavage involved in gene silencing by miRNA