Planteome: Term Details for "miRNA-mediated gene silencing by mRNA destabilization" (GO:0035279)

Term Information

Accession: GO:0035279
Name: miRNA-mediated gene silencing by mRNA destabilization
Ontology: biological_process
Synonyms: gene silencing by miRNA, mRNA cleavage, mRNA cleavage involved in gene silencing by miRNA, mRNA cleavage involved in gene silencing by microRNA, mRNA destabilization-mediated gene silencing by miRNA, miRNA-mediated gene silencing, mRNA cleavage, deadenylation involved in gene silencing by miRNA, mRNA deadenylation-mediated gene silencing by miRNA, miRNA-mediated gene silencing by mRNA deadenylation, gene silencing by mRNA cleavage
Alternate IDs: None
Definition: An RNA interference pathway in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism. Source: GOC:dph, PMID:15196554, GOC:mtg_lung, PMID:14744438, PMID:21118121, PMID:23209154
Comment: None
History: See term history for GO:0035279 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to miRNA-mediated gene silencing by mRNA destabilization.; Link to all direct and indirect annotations to miRNA-mediated gene silencing by mRNA destabilization.; Link to all direct and indirect annotations download (limited to first 10,000) for miRNA-mediated gene silencing by mRNA destabilization.
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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BFO:0000001 entity
BFO:0000003 occurrent
GO:0065007 biological regulation
GO:0008150 biological_process
GO:0044249 cellular biosynthetic process
GO:0044237 cellular metabolic process
GO:0034641 cellular nitrogen compound metabolic process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0006807 nitrogen compound metabolic process
GO:0071704 organic substance metabolic process
BFO:0000015 process
GO:0050789 regulation of biological process
GO:0043603 amide metabolic process
GO:0009058 biosynthetic process
GO:0009056 catabolic process
GO:0006725 cellular aromatic compound metabolic process
GO:0044248 cellular catabolic process
GO:0044271 cellular nitrogen compound biosynthetic process
GO:0046483 heterocycle metabolic process
GO:0043170 macromolecule metabolic process
GO:0048519 negative regulation of biological process
GO:0006139 nucleobase-containing compound metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:1901575 organic substance catabolic process
GO:1901564 organonitrogen compound metabolic process
GO:0048518 positive regulation of biological process
GO:0009893 positive regulation of metabolic process
GO:0044238 primary metabolic process
GO:0031323 regulation of cellular metabolic process
GO:0050794 regulation of cellular process
GO:0019222 regulation of metabolic process
GO:0051171 regulation of nitrogen compound metabolic process
GO:0080090 regulation of primary metabolic process
GO:0043604 amide biosynthetic process
GO:0019439 aromatic compound catabolic process
GO:0044270 cellular nitrogen compound catabolic process
GO:0010467 gene expression
GO:0046700 heterocycle catabolic process
GO:0009059 macromolecule biosynthetic process
GO:0016071 mRNA metabolic process
GO:0048523 negative regulation of cellular process
GO:0009892 negative regulation of metabolic process
GO:0090304 nucleic acid metabolic process
GO:1901361 organic cyclic compound catabolic process
GO:1901566 organonitrogen compound biosynthetic process
GO:0006518 peptide metabolic process
GO:0031325 positive regulation of cellular metabolic process
GO:0048522 positive regulation of cellular process
GO:0051173 positive regulation of nitrogen compound metabolic process
GO:0019538 protein metabolic process
GO:0009889 regulation of biosynthetic process
GO:0009894 regulation of catabolic process
GO:0010468 regulation of gene expression
GO:0060255 regulation of macromolecule metabolic process
GO:0019219 regulation of nucleobase-containing compound metabolic process
GO:0051252 regulation of RNA metabolic process
GO:0016070 RNA metabolic process
GO:0009057 macromolecule catabolic process
GO:0006402 mRNA catabolic process
GO:0009890 negative regulation of biosynthetic process
GO:0031324 negative regulation of cellular metabolic process
GO:0010629 negative regulation of gene expression
GO:0010605 negative regulation of macromolecule metabolic process
GO:0051172 negative regulation of nitrogen compound metabolic process
GO:0034655 nucleobase-containing compound catabolic process
GO:0043043 peptide biosynthetic process
GO:0009896 positive regulation of catabolic process
GO:0010604 positive regulation of macromolecule metabolic process
GO:0045935 positive regulation of nucleobase-containing compound metabolic process
GO:0051254 positive regulation of RNA metabolic process
GO:0010608 post-transcriptional regulation of gene expression
GO:0034248 regulation of amide metabolic process
GO:0065008 regulation of biological quality
GO:0031326 regulation of cellular biosynthetic process
GO:0031329 regulation of cellular catabolic process
GO:0010556 regulation of macromolecule biosynthetic process
GO:1903311 regulation of mRNA metabolic process
GO:0051246 regulation of protein metabolic process
GO:0006401 RNA catabolic process
GO:0006412 translation
GO:0034249 negative regulation of amide metabolic process
GO:0031327 negative regulation of cellular biosynthetic process
GO:0010558 negative regulation of macromolecule biosynthetic process
GO:0051248 negative regulation of protein metabolic process
GO:0031331 positive regulation of cellular catabolic process
GO:1903313 positive regulation of mRNA metabolic process
GO:0016441 post-transcriptional gene silencing
GO:0061013 regulation of mRNA catabolic process
GO:0043487 regulation of RNA stability
GO:0006417 regulation of translation
GO:0031047 regulatory ncRNA-mediated gene silencing
GO:0017148 negative regulation of translation
GO:0061014 positive regulation of mRNA catabolic process
GO:0043488 regulation of mRNA stability
GO:0035194 regulatory ncRNA-mediated post-transcriptional gene silencing
GO:0050779 RNA destabilization
GO:0035195 miRNA-mediated gene silencing
GO:0061157 mRNA destabilization
GO:0035279 miRNA-mediated gene silencing by mRNA destabilization
GO:0090624 endoribonuclease activity, cleaving miRNA-paired mRNA

Parents of miRNA-mediated gene silencing by mRNA destabilization (GO:0035279)

subject	relation	object
miRNA-mediated gene silencing by mRNA destabilization	is_a	miRNA-mediated gene silencing (GO:0035195)
miRNA-mediated gene silencing by mRNA destabilization	is_a	mRNA destabilization (GO:0061157)

Children of miRNA-mediated gene silencing by mRNA destabilization (GO:0035279)

subject	relation	object
endoribonuclease activity, cleaving miRNA-paired mRNA (GO:0090624)	BFO:0000050	miRNA-mediated gene silencing by mRNA destabilization

miRNA-mediated gene silencing by mRNA destabilization

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Parents of miRNA-mediated gene silencing by mRNA destabilization (GO:0035279)

Children of miRNA-mediated gene silencing by mRNA destabilization (GO:0035279)

None.