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Term Information

Accession
GO:0035708
Name
interleukin-4-dependent isotype switching to IgE isotypes
Ontology
biological_process
Synonyms
IL-4-dependent isotype switching to IgE isotypes
Alternate IDs
None
Definition
The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus, that is dependent on the activity of interleukin 4 (IL-4). Source: GOC:BHF, PMID:12496423
Comment
None
History
See term history for GO:0035708 at QuickGO
Subset
None
Feedback
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Graph of GO:0035708

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Parents of interleukin-4-dependent isotype switching to IgE isotypes (GO:0035708)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
interleukin-4-dependent isotype switching to IgE isotypes [is_a relation] is_a  isotype switching to IgE isotypes (GO:0048289)
Children of interleukin-4-dependent isotype switching to IgE isotypes (GO:0035708)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of interleukin-4-dependent isotype switching to IgE isotypes (GO:2000571) [RO:0002211 relation] RO:0002211  interleukin-4-dependent isotype switching to IgE isotypes
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes (GO:2000572) [RO:0002213 relation] RO:0002213  interleukin-4-dependent isotype switching to IgE isotypes
None.