Planteome: Term Details for "Kit signaling pathway" (GO:0038109)

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Term Information

Accession: GO:0038109
Name: Kit signaling pathway
Ontology: biological_process
Synonyms: Kit signalling pathway, SCF signaling pathway, stem cell factor receptor signaling pathway, stem cell factor signaling pathway
Alternate IDs: None
Definition: The series of molecular signals initiated by the binding of stem cell factor to the tyrosine kinase receptor KIT on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Stem cell factor (KIT ligand) binding to the receptor Kit mediates receptor dimerization, activation of its intrinsic tyrosine kinase activity and autophosphorylation. The activated receptor then phosphorylates various substrates, thereby activating distinct signaling cascades within the cell that trigger a change in state or activity of the cell. Source: GOC:signaling, GOC:nhn, PMID:16129412
Comment: None
History: See term history for GO:0038109 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to Kit signaling pathway.; Link to all direct and indirect annotations to Kit signaling pathway.; Link to all direct and indirect annotations download (limited to first 10,000) for Kit signaling pathway.
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BFO:0000001 entity
BFO:0000003 occurrent
GO:0008150 biological_process
GO:0065007 biological regulation
BFO:0000015 process
GO:0050896 response to stimulus
GO:0009987 cellular process
GO:0051716 cellular response to stimulus
GO:0050789 regulation of biological process
GO:0042221 response to chemical
GO:0007154 cell communication
GO:0070887 cellular response to chemical stimulus
GO:0050794 regulation of cellular process
GO:0010033 response to organic substance
GO:0023052 signaling
GO:0007166 cell surface receptor signaling pathway
GO:0071310 cellular response to organic substance
GO:0034097 response to cytokine
GO:0007165 signal transduction
GO:0071345 cellular response to cytokine stimulus
GO:0007167 enzyme-linked receptor protein signaling pathway
GO:0036215 response to stem cell factor
GO:0036216 cellular response to stem cell factor stimulus
GO:0019221 cytokine-mediated signaling pathway
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0038109 Kit signaling pathway
GO:1900235 negative regulation of Kit signaling pathway
GO:1900236 positive regulation of Kit signaling pathway
GO:1900234 regulation of Kit signaling pathway
GO:0005020 stem cell factor receptor activity

Parents of Kit signaling pathway (GO:0038109)

subject	relation	object
Kit signaling pathway	BFO:0000050	cellular response to stem cell factor stimulus (GO:0036216)
Kit signaling pathway	is_a	cytokine-mediated signaling pathway (GO:0019221)
Kit signaling pathway	is_a	transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169)

Children of Kit signaling pathway (GO:0038109)

subject	relation	object
positive regulation of Kit signaling pathway (GO:1900236)	RO:0002213	Kit signaling pathway
stem cell factor receptor activity (GO:0005020)	BFO:0000050	Kit signaling pathway
regulation of Kit signaling pathway (GO:1900234)	RO:0002211	Kit signaling pathway
negative regulation of Kit signaling pathway (GO:1900235)	RO:0002212	Kit signaling pathway