You are using the Cyverse mirror of the Planteome Ontology Browser. The main site is at browser.planteome.org.

Term Information

Accession
GO:0039528
Name
cytoplasmic pattern recognition receptor signaling pathway in response to virus
Ontology
biological_process
Synonyms
cytoplasmic pattern recognition receptor signalling pathway in response to virus, virus-induced cytoplasmic pattern recognition receptor signaling pathway, RIG-I-like receptor (RLR) signaling pathway, RIG-I/MDA5 signaling pathway, RIG-like helicase signaling pathway, RIG-like receptor signaling pathway, RLH signaling pathway, RLR signaling pathway, cytoplasmic caspase-recruiting domain (CARD) helicase signaling pathway
Alternate IDs
None
Definition
Any series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. Cytosolic PRRs such as RIG-I (DDX58) and MDA-5 (IFIH1) detect RNA synthesized during active viral replication and trigger a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. Source: PMID:18272355, GOC:bf, PMID:19531363, PMID:17328678
Comment
This term should be used for annotation when it is not known which cytoplasmic pattern recognition receptor (PRR) has detected the viral RNA. If the PRR is known, consider instead the child terms. The RIG-like family is composed of at least RIG-I (retinoic acid inducible gene I; also known as DDX58), melanoma differentiation-associated gene 5 (MDA5; also known as helicard or IFIH1) and LGP2.
History
See term history for GO:0039528 at QuickGO
Subset
None
Feedback
Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
External term view.

Graph of GO:0039528

Viewing options
Parents of cytoplasmic pattern recognition receptor signaling pathway in response to virus (GO:0039528)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cytoplasmic pattern recognition receptor signaling pathway in response to virus [is_a relation] is_a  cellular response to virus (GO:0098586)
cytoplasmic pattern recognition receptor signaling pathway in response to virus [BFO:0000050 relation] BFO:0000050  defense response to virus (GO:0051607)
cytoplasmic pattern recognition receptor signaling pathway in response to virus [is_a relation] is_a  cytoplasmic pattern recognition receptor signaling pathway (GO:0002753)
cytoplasmic pattern recognition receptor signaling pathway in response to virus [is_a relation] is_a  positive regulation of cytokine production (GO:0001819)
Children of cytoplasmic pattern recognition receptor signaling pathway in response to virus (GO:0039528)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) [RO:0002211 relation] RO:0002211  cytoplasmic pattern recognition receptor signaling pathway in response to virus
RIG-I signaling pathway (GO:0039529) [is_a relation] is_a  cytoplasmic pattern recognition receptor signaling pathway in response to virus
negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039532) [RO:0002212 relation] RO:0002212  cytoplasmic pattern recognition receptor signaling pathway in response to virus
MDA-5 signaling pathway (GO:0039530) [is_a relation] is_a  cytoplasmic pattern recognition receptor signaling pathway in response to virus
None.