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Term Information

Accession
GO:0043111
Name
replication fork arrest
Ontology
biological_process
Synonyms
negative regulation of DNA replication at replication fork barrier, replication fork blocking, replication fork stalling
Alternate IDs
None
Definition
Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected. Source: PMID:14645529, GOC:jl, GOC:pr
Comment
See also the biological process term 'site-specific replication termination ; GO:0071170' and its children.
History
See term history for GO:0043111 at QuickGO
Subset
None
Feedback
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Graph of GO:0043111

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Parents of replication fork arrest (GO:0043111)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
replication fork arrest [is_a relation] is_a  negative regulation of DNA-templated DNA replication (GO:2000104)
replication fork arrest [is_a relation] is_a  DNA-templated DNA replication maintenance of fidelity (GO:0045005)
Children of replication fork arrest (GO:0043111)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
replication fork arrest at tRNA locus (GO:0090001) [is_a relation] is_a  replication fork arrest
replication fork arrest at rDNA repeats (GO:0031582) [is_a relation] is_a  replication fork arrest
replication fork arrest at mating type locus (GO:0011000) [is_a relation] is_a  replication fork arrest
replication fork arrest involved in DNA replication termination (GO:0071807) [is_a relation] is_a  replication fork arrest
None.