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cytoplasmic SCF ubiquitin ligase complex

Term Information

Accession
GO:0043223
Name
cytoplasmic SCF ubiquitin ligase complex
Ontology
cellular_component
Synonyms
cytoplasmic SCF complex, cytoplasmic Skp1/Cul1/F-box protein complex, cytoplasmic cullin complex
Alternate IDs
None
Definition
A ubiquitin ligase complex, located in the cytoplasm, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1). Source: PMID:15688063, PMID:15571813
Comment
None
History
See term history for GO:0043223 at QuickGO
Subset
None
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Graph of GO:0043223

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Parents of cytoplasmic SCF ubiquitin ligase complex (GO:0043223)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cytoplasmic SCF ubiquitin ligase complex [is_a relation] is_a  cytoplasmic ubiquitin ligase complex (GO:0000153)
cytoplasmic SCF ubiquitin ligase complex [is_a relation] is_a  SCF ubiquitin ligase complex (GO:0019005)
cytoplasmic SCF ubiquitin ligase complex [BFO:0000050 relation] BFO:0000050  cytoplasm (GO:0005737)

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