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Ku70:Ku80 complex
Term Information
Accession
GO:0043564
Name
Ku70:Ku80 complex
Ontology
cellular_component
Synonyms
Ku70:Ku80 heterodimer
Alternate IDs
None
Definition
Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK.
Source:PMID:12518983
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