Planteome: Term Details for "leukocyte tethering or rolling" (GO:0050901)

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Term Information

Accession: GO:0050901
Name: leukocyte tethering or rolling
Ontology: biological_process
Synonyms: None
Alternate IDs: None
Definition: Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection). Source: PMID:8600538, PMID:7507411, ISBN:0781735149, PMID:14680625, GOC:bf, Wikipedia:Leukocyte_extravasation, PMID:14708592
Comment: None
History: See term history for GO:0050901 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to leukocyte tethering or rolling.; Link to all direct and indirect annotations to leukocyte tethering or rolling.; Link to all direct and indirect annotations download (limited to first 10,000) for leukocyte tethering or rolling.
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BFO:0000001 entity
BFO:0000003 occurrent
GO:0008150 biological_process
GO:0009987 cellular process
BFO:0000015 process
GO:0007155 cell adhesion
GO:0048870 cell motility
GO:0016477 cell migration
GO:0098609 cell-cell adhesion
GO:0002376 immune system process
GO:0007159 leukocyte cell-cell adhesion
GO:0050900 leukocyte migration
GO:0045123 cellular extravasation
GO:0061756 leukocyte adhesion to vascular endothelial cell
GO:0050901 leukocyte tethering or rolling
GO:1903237 negative regulation of leukocyte tethering or rolling
GO:1903238 positive regulation of leukocyte tethering or rolling
GO:1903236 regulation of leukocyte tethering or rolling

Parents of leukocyte tethering or rolling (GO:0050901)

subject	relation	object
leukocyte tethering or rolling	is_a	leukocyte adhesion to vascular endothelial cell (GO:0061756)
leukocyte tethering or rolling	BFO:0000050	cellular extravasation (GO:0045123)

Children of leukocyte tethering or rolling (GO:0050901)

subject	relation	object
regulation of leukocyte tethering or rolling (GO:1903236)	RO:0002211	leukocyte tethering or rolling
positive regulation of leukocyte tethering or rolling (GO:1903238)	RO:0002213	leukocyte tethering or rolling
negative regulation of leukocyte tethering or rolling (GO:1903237)	RO:0002212	leukocyte tethering or rolling