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Term Information

Accession
GO:0060087
Name
relaxation of vascular associated smooth muscle
Ontology
biological_process
Synonyms
relaxation of vascular smooth muscle, vascular smooth muscle relaxation, negative regulation of relaxation of vascular smooth muscle, positive regulation of relaxation of vascular smooth muscle, regulation of relaxation of vascular smooth muscle
Alternate IDs
GO:1905657, GO:1905658, GO:1905659
Definition
A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity. Source: GOC:BHF_miRNA, GOC:rph, GOC:dph, PMID:15867178, GOC:BHF, GOC:TermGenie, GO_REF:0000058, PMID:27389411, PMID:19996365
Comment
None
History
See term history for GO:0060087 at QuickGO
Subset
None
Feedback
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Graph of GO:0060087

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Parents of relaxation of vascular associated smooth muscle (GO:0060087)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
relaxation of vascular associated smooth muscle [BFO:0000050 relation] BFO:0000050  vasodilation (GO:0042311)
relaxation of vascular associated smooth muscle [is_a relation] is_a  negative regulation of smooth muscle contraction (GO:0045986)
relaxation of vascular associated smooth muscle [is_a relation] is_a  relaxation of smooth muscle (GO:0044557)

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