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Term Information

Accession
GO:0061684
Name
chaperone-mediated autophagy
Ontology
biological_process
Synonyms
chaperone-assisted selective autophagy, CASA, CMA
Alternate IDs
None
Definition
The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded. Source: GOC:PARL, PMID:22743996, GOC:pad, PMID:23434281
Comment
None
History
See term history for GO:0061684 at QuickGO
Subset
None
Feedback
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Graph of GO:0061684

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Parents of chaperone-mediated autophagy (GO:0061684)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
chaperone-mediated autophagy [BFO:0000051 relation] BFO:0000051  signaling receptor binding (GO:0005102)
chaperone-mediated autophagy [is_a relation] is_a  autophagy (GO:0006914)
chaperone-mediated autophagy [BFO:0000051 relation] BFO:0000051  chaperone-mediated protein transport (GO:0072321)
chaperone-mediated autophagy [is_a relation] is_a  protein catabolic process (GO:0030163)
Children of chaperone-mediated autophagy (GO:0061684)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of chaperone-mediated autophagy (GO:1904716) [RO:0002213 relation] RO:0002213  chaperone-mediated autophagy
chaperone-mediated autophagy translocation complex assembly (GO:1904763) [BFO:0000050 relation] BFO:0000050  chaperone-mediated autophagy
chaperone-mediated protein transport involved in chaperone-mediated autophagy (GO:0061741) [BFO:0000050 relation] BFO:0000050  chaperone-mediated autophagy
negative regulation of chaperone-mediated autophagy (GO:1904715) [RO:0002212 relation] RO:0002212  chaperone-mediated autophagy
protein targeting to lysosome involved in chaperone-mediated autophagy (GO:0061740) [BFO:0000050 relation] BFO:0000050  chaperone-mediated autophagy
regulation of chaperone-mediated autophagy (GO:1904714) [RO:0002211 relation] RO:0002211  chaperone-mediated autophagy