Planteome: Term Details for "shelterin complex" (GO:0070187)

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Term Information

Accession: GO:0070187
Name: shelterin complex
Ontology: cellular_component
Synonyms: Pot1 complex, Pot1-Tpz1 complex, telosome
Alternate IDs: None
Definition: A nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase. The complex is known to contain TERF1, TERF2, POT1, RAP1, TINF2 and ACD in mammalian cells, and Pot1, Tpz1, Rap1, Rif1, Rif2 and Taz1 in Saccharomyces. Taz1 and Rap1 (or their mammalian equivalents) form a dsDNA-binding subcomplex, Pot1 and Tpz1 form an ssDNA-binding subcomplex, and the two subcomplexes are bridged by Poz1, which acts as an effector molecule along with Ccq1. Source: PMID:18828880, GOC:expert_mf, GOC:vw, GOC:mah
Comment: None
History: See term history for GO:0070187 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to shelterin complex.; Link to all direct and indirect annotations to shelterin complex.; Link to all direct and indirect annotations download (limited to first 10,000) for shelterin complex.
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