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Term Information

Accession
GO:0070478
Name
nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay
Ontology
biological_process
Synonyms
3'-5' NMD, 3'-5' nonsense-mediated decay, 3'-5' nonsense-mediated mRNA decay, nuclear-transcribed mRNA breakdown, 3'-5' exonucleolytic nonsense-mediated decay, nuclear-transcribed mRNA catabolism, 3'-5' exonucleolytic nonsense-mediated decay, nuclear-transcribed mRNA degradation, 3'-5' exonucleolytic nonsense-mediated decay
Alternate IDs
None
Definition
The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction. Source: PMID:12769863
Comment
None
History
See term history for GO:0070478 at QuickGO
Subset
None
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Graph of GO:0070478

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Parents of nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay (GO:0070478)
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nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [is_a relation] is_a  nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' (GO:0034427)
nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [is_a relation] is_a  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)

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