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Term Information

Accession
GO:0070744
Name
interleukin-27 complex
Ontology
cellular_component
Synonyms
IL-27 complex, EBI3, IL27, p28
Alternate IDs
None
Definition
A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space. Source: GOC:add, PMID:15999093, PMID:19161428
Comment
Note that this heterodimeric cytokine utilizes the same EBI3 subunit (product of EBI3, Epstein-Barr virus induced gene 3) as its beta chain as IL-35 uses for its beta chain. Also note that the product of the IL27 gene is the alpha subunit of IL-27. The functional IL-27 protein complex requires both subunits.
History
See term history for GO:0070744 at QuickGO
Subset
None
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Graph of GO:0070744

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Parents of interleukin-27 complex (GO:0070744)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
interleukin-27 complex [BFO:0000050 relation] BFO:0000050  extracellular space (GO:0005615)
interleukin-27 complex [is_a relation] is_a  protein-containing complex (GO:0032991)

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