Planteome: Term Details for "interleukin-35 complex" (GO:0070745)

Accession: GO:0070745
Name: interleukin-35 complex
Ontology: cellular_component
Synonyms: IL-35 complex, EBI3, IL12A, p35
Alternate IDs: None
Definition: A protein complex that is composed of an interleukin-12 alpha subunit (p35, product of the IL12A gene) and an EBI3 subunit and is secreted into the extracellular space. Source: GOC:add, PMID:19161429, PMID:19161428
Comment: Note that this heterodimeric cytokine utilizes the same IL-12p35 subunit as its alpha chain as IL-12 uses and the same EBI3 subunit (product of EBI3, Epstein-Barr virus induced gene 3) as its beta chain as IL-27 uses. IL-35 requires both subunits -- there is no separate IL35 gene.
History: See term history for GO:0070745 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to interleukin-35 complex.; Link to all direct and indirect annotations to interleukin-35 complex.; Link to all direct and indirect annotations download (limited to first 10,000) for interleukin-35 complex.
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