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Term Information

Accession
GO:0090555
Name
phosphatidylethanolamine flippase activity
Ontology
molecular_function
Synonyms
phosphatidylethanolamine flippase activity (exoplasmic to cytosolic leaftlet), ATP-dependent phosphatidylethanolamine transporter activity, phosphatidylethanolamine-translocating ATPase activity, ATPase-coupled phosphatidylethanolamine transporter activity
Alternate IDs
None
Definition
Catalysis of the movement of phosphatidylethanolamine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. Source: PMID:16452632, GOC:ab, PMID:20043909, RHEA:36440
Comment
Nomenclature note. Flippases and floppases are ATP-dependent transbilayer lipid translocators. According to an extensively used, though not universal, nomenclature, they catalyze lipid transfer towards the inward monolayer (flippases) or towards the outward monolayer (floppases). Scramblases are ATP-independent, non-selective, inducing non-specific transbilayer movements across the membrane. The direction of the translocation should be taken into account for annotation (from the exoplasmic to the cytosolic leaftlet of a membrane).
History
See term history for GO:0090555 at QuickGO
Subset
None
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Parents of phosphatidylethanolamine flippase activity (GO:0090555)
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phosphatidylethanolamine flippase activity [is_a relation] is_a  glycerophospholipid flippase activity (GO:0140333)

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RHEA
66132