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Term Information

Accession
GO:0140080
Name
class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity
Ontology
molecular_function
Synonyms
endonuclease III, endonuclease IV
Alternate IDs
None
Definition
Catalysis of the cleavage of an AP site 3' and 5' of the baseless site, generating a 3'-phosphate and a 5'-OH. Source: PMID:2519777
Comment
Note that this term is does not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis. Class II AP endonuclease is a nuclease, but not Class I, III and IV.
History
See term history for GO:0140080 at QuickGO
Subset
None
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Graph of GO:0140080

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Parents of class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity (GO:0140080)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity [is_a relation] is_a  DNA-(apurinic or apyrimidinic site) endonuclease activity (GO:0003906)

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Wikipedia
AP_endonuclease