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Term Information

Accession
GO:0140261
Name
BCOR complex
Ontology
cellular_component
Synonyms
BCL6 corepressor (BCOR) complex, BCOR/BCORL1 complex, PRC1.1 complex, non-canonical BCOR-PRC1.1 complex, non-canonical PRC1-BCOR complex
Alternate IDs
None
Definition
A protein-containing complex that monoubiquitinates histone H2A on K119, thus it facilitates the maintenance of the transcriptionally repressive state of some genes, such as BCL6. It consists of the corepressor BCOR or BCORL1, a Polycomb group (PcG) and a SCF ubiquitin ligase subcomplexes. In mammals, the core subunits of the complex include the PcG and PcG-associated proteins NSPC1, RING1, RNF2, and RYBP and the components of the SCF ubiquitin ligase, SKP1, and FBXL10. Source: PMID:16943429, PMID:22325352, PMID:24515802
Comment
None
History
See term history for GO:0140261 at QuickGO
Subset
None
Feedback
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Graph of GO:0140261

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Parents of BCOR complex (GO:0140261)
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BCOR complex [is_a relation] is_a  nuclear ubiquitin ligase complex (GO:0000152)

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