Planteome: Term Details for "DNA-binding transcription factor inhibitor activity" (GO:0140416)

Accession: GO:0140416
Name: DNA-binding transcription factor inhibitor activity
Ontology: molecular_function
Synonyms: None
Alternate IDs: None
Definition: An activity that stops, prevents, or reduces the activity of a DNA binding transcription factor activity. Source: PMID:10652346
Comment: An example is TCF23 Q7RTU1 is an example of a protein that regulates transcription factors by heterodimerising or binding to DbTFs and prevent DNA binding and their specific genomic binding site where the dbTF would have activated or repressed transcription. Also an example is NFKBIA P25963 which has a different way of regulating transcription factor activity by sequestering the dbTF (complex) in the cytoplasm. Another example is the HSP90 and HSP23 proteins that sequester steroid receptors away from the DNA.
History: See term history for GO:0140416 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to DNA-binding transcription factor inhibitor activity.; Link to all direct and indirect annotations to DNA-binding transcription factor inhibitor activity.; Link to all direct and indirect annotations download (limited to first 10,000) for DNA-binding transcription factor inhibitor activity.
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