Planteome: Term Details for "MCM complex loading" (GO:0140530)

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Term Information

Accession: GO:0140530
Name: MCM complex loading
Ontology: biological_process
Synonyms: MCM complex loading at replication origin, MCM double hexamer formation at replication origin
Alternate IDs: None
Definition: The protein localization process in which two MCM complexes become associated with chromatin at replication origins. MCM loading begins when origin-bound ORC and Cdc6 (Cdc18 in fission yeast) recruit one MCM2-7/Cdt1 complex to the origin, includes formation of a succession of intermediate complexes and ATP hydrolysis-dependent Mcm2-7 ring closure, and ends when two MCM hexamers fully encircle DNA, and are oriented head-to-head. The double hexamer is inactive for DNA unwinding. MCM loading takes place during G1 phase, and precedes CMG complex assembly. Source: PMID:28501329, PMID:23603117, PMID:28191893, PMID:28191894
Comment: None
History: See term history for GO:0140530 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to MCM complex loading.; Link to all direct and indirect annotations to MCM complex loading.; Link to all direct and indirect annotations download (limited to first 10,000) for MCM complex loading.
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GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0044237 cellular metabolic process
GO:0005575 cellular_component
GO:0006807 nitrogen compound metabolic process
GO:0071704 organic substance metabolic process
GO:0110165 cellular anatomical entity
GO:0006725 cellular aromatic compound metabolic process
GO:0034641 cellular nitrogen compound metabolic process
GO:0046483 heterocycle metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:0044238 primary metabolic process
GO:0006259 DNA metabolic process
BFO:0000001 entity
GO:0005622 intracellular anatomical structure
GO:0043170 macromolecule metabolic process
GO:0006139 nucleobase-containing compound metabolic process
BFO:0000003 occurrent
GO:0043226 organelle
GO:0071840 cellular component organization or biogenesis
GO:0006260 DNA replication
GO:0043229 intracellular organelle
GO:0043227 membrane-bounded organelle
GO:0090304 nucleic acid metabolic process
GO:0022402 cell cycle process
GO:0044085 cellular component biogenesis
GO:0016043 cellular component organization
GO:0006261 DNA-templated DNA replication
GO:0043231 intracellular membrane-bounded organelle
BFO:0000015 process
GO:0044786 cell cycle DNA replication
GO:0022607 cellular component assembly
GO:0006270 DNA replication initiation
GO:0005634 nucleus
GO:0043933 protein-containing complex organization
GO:0007049 cell cycle
GO:1902292 cell cycle DNA replication initiation
GO:0033260 nuclear DNA replication
GO:0065003 protein-containing complex assembly
GO:0071824 protein-DNA complex organization
GO:1902315 nuclear cell cycle DNA replication initiation
GO:0065004 protein-DNA complex assembly
GO:0140530 MCM complex loading

Parents of MCM complex loading (GO:0140530)

subject	relation	object
MCM complex loading	is_a	cell cycle process (GO:0022402)
MCM complex loading	BFO:0000050	nuclear cell cycle DNA replication initiation (GO:1902315)
MCM complex loading	is_a	protein-DNA complex assembly (GO:0065004)

This term has no children.

MCM complex loading

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Parents of MCM complex loading (GO:0140530)

None.