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Term Information

Accession
GO:0140735
Name
lovastatin biosynthetic process
Ontology
biological_process
Synonyms
lovastatin anabolism, lovastatin biosynthesis, lovastatin formation, lovastatin synthesis, mevacor anabolism, mevacor biosynthesis, mevacor biosynthetic process, mevacor formation, mevacor synthesis, mevinolin anabolism, mevinolin biosynthesis, mevinolin biosynthetic process, mevinolin formation,, mevinolin synthesis, monacolin K anabolism, monacolin K biosynthesis, monacolin K biosynthetic process, monacolin K formation, monacolin K synthesis
Alternate IDs
None
Definition
The chemical reactions and pathways resulting in the formation of lovastatin (also known as mevinolin, mevacor or monacolin K), a hypolipidemic inhibitor of (3S)-hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR). Source: PMID:10334994, PMID:10381407
Comment
None
History
See term history for GO:0140735 at QuickGO
Subset
None
Feedback
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Graph of GO:0140735

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Parents of lovastatin biosynthetic process (GO:0140735)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
lovastatin biosynthetic process [is_a relation] is_a  fatty acid derivative biosynthetic process (GO:1901570)
lovastatin biosynthetic process [is_a relation] is_a  polyketide biosynthetic process (GO:0030639)
lovastatin biosynthetic process [is_a relation] is_a  lactone biosynthetic process (GO:1901336)
lovastatin biosynthetic process [is_a relation] is_a  mycotoxin biosynthetic process (GO:0043386)
Children of lovastatin biosynthetic process (GO:0140735)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of lovastatin biosynthetic process (GO:0140736) [RO:0002213 relation] RO:0002213  lovastatin biosynthetic process
kegg.module
M00893
MetaCyc
PWY-7535