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Term Information

Accession
GO:0140750
Name
nucleosome array spacer activity
Ontology
molecular_function
Synonyms
nucleosome array spacing activity
Alternate IDs
None
Definition
A histone octamer slider activity that spaces nucleosomes along chromosomal DNA. This activity is involved in assembling chromatin in uniform nucleosome arrays to regulate transcription by RNA polymerases I, II, and III, as well as DNA replication, recombination and repair. Source: PMID:11683384, PMID:16468993
Comment
In Drosphila, this is mediated by ISWI, in human, by SMARCA5 and in S. cerevisiae by ISW1 and and ISW2.
History
See term history for GO:0140750 at QuickGO
Subset
None
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Graph of GO:0140750

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Parents of nucleosome array spacer activity (GO:0140750)
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nucleosome array spacer activity [is_a relation] is_a  histone octamer slider activity (GO:0140751)

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