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Term Information

Accession
GO:0140911
Name
pore-forming activity
Ontology
molecular_function
Synonyms
pore forming activity, canonical holin activity, holin activity, pinholin activity
Alternate IDs
GO:0034292, GO:0034290, GO:0034291
Definition
An activity in which a protein is inserted into the membrane of another cell where it forms transmembrane pores. Pores disrupts the integrity of the cell membrane, resulting in deregulated ion homeostasis, cellular dysfunction, and can result in cell death. Source: PMID:34387717, PMID:1406491, PMID:25157079
Comment
None
History
See term history for GO:0140911 at QuickGO
Subset
None
Feedback
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Parents of pore-forming activity (GO:0140911)
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pore-forming activity [is_a relation] is_a  molecular_function (GO:0003674)

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TC
1.C