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Term Information

Accession
GO:0140991
Name
piRNA-mediated gene silencing by mRNA destabilization
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
A cytoplasmic post-transcriptional gene silencing pathway in which piRNAs direct the cleavage of target mRNAs. The target mRNA, often transcribed from a transposable element, is destabilized by the activity of a PIWI class endonuclease within the piRNA-induced silencing complex. This may also be accompanied by mRNA deadenylation and decapping. Source: PMID:29281264, PMID:33419460
Comment
None
History
See term history for GO:0140991 at QuickGO
Subset
None
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Parents of piRNA-mediated gene silencing by mRNA destabilization (GO:0140991)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
piRNA-mediated gene silencing by mRNA destabilization [is_a relation] is_a  mRNA destabilization (GO:0061157)
piRNA-mediated gene silencing by mRNA destabilization [is_a relation] is_a  regulatory ncRNA-mediated post-transcriptional gene silencing (GO:0035194)

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None.