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transcription-coupled nucleotide-excision repair, DNA damage recognition complex
Term Information
Accession
GO:1990250
Name
transcription-coupled nucleotide-excision repair, DNA damage recognition complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A protein complex that is capable of identifying lesions in DNA on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex.
Source:PMID:22331906,
GOC:bhm
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