Planteome: Term Details for "Bre1-Rad6 ubiquitin ligase complex" (GO:1990302)

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Term Information

Accession: GO:1990302
Name: Bre1-Rad6 ubiquitin ligase complex
Ontology: cellular_component
Synonyms: Bre1-Rad6 complex
Alternate IDs: None
Definition: A ubiquitin ligase complex consisting of Bre1 and Rad6 that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. It thereby plays a central role in histone code and gene regulation. It also modulates the formation of double-strand breaks during meiosis. Source: PMID:19531475, GOC:bhm
Comment: This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:19531475 (inferred from direct assay).
History: See term history for GO:1990302 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to Bre1-Rad6 ubiquitin ligase complex.; Link to all direct and indirect annotations to Bre1-Rad6 ubiquitin ligase complex.; Link to all direct and indirect annotations download (limited to first 10,000) for Bre1-Rad6 ubiquitin ligase complex.
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GO:0005575 cellular_component
GO:0032991 protein-containing complex
GO:1902494 catalytic complex
GO:0110165 cellular anatomical entity
GO:0005622 intracellular anatomical structure
GO:1990234 transferase complex
GO:1990302 Bre1-Rad6 ubiquitin ligase complex

Parents of Bre1-Rad6 ubiquitin ligase complex (GO:1990302)

subject	relation	object
Bre1-Rad6 ubiquitin ligase complex	BFO:0000050	intracellular anatomical structure (GO:0005622)
Bre1-Rad6 ubiquitin ligase complex	is_a	transferase complex (GO:1990234)

This term has no children.

IntAct: EBI-9102228