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Term Information

Accession
GO:1990566
Name
I(KACh) inward rectifier potassium channel complex
Ontology
cellular_component
Synonyms
GIRK1-GIRK4 G protein-coupled atrial inward rectifier potassium channel complex, Kir3.1-Kir3.4 G protein-coupled atrial inward rectifier potassium channel complex, muscarinic potassium channel complex
Alternate IDs
None
Definition
An inward rectifier potassium channel complex expressed in cardiac muscle, specifically the sinoatrial node and atria, where it controls the heart rate, via regulation by G protein-coupled receptor signalling. In mammals it is composed of GIRK1 (or Kir3.1) and GIRK4 (or Kir3.4) subunits. Source: PMID:9765280, GOC:ame
Comment
Examples of this are KCNJ3 and KCNJ5 in human (Uniprot symbols P48549 and P48544) in PMID:9765280 inferred from orthology sequence evidence.
History
See term history for GO:1990566 at QuickGO
Subset
None
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Parents of I(KACh) inward rectifier potassium channel complex (GO:1990566)
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I(KACh) inward rectifier potassium channel complex [is_a relation] is_a  inward rectifier potassium channel complex (GO:1902937)

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