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ATF4-CREB1 transcription factor complex
Term Information
Accession
GO:1990589
Name
ATF4-CREB1 transcription factor complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
Transcription factor complex consisting of ATF4 and CREB1 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') as part of the positive regulation of transcription. Regulatory targets include the GRP78 (HSPA5) promoter in humans, whose activation by this complex is part of the ER stress response pathway.
Source:PMID:12871976,
GOC:bhm
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