Planteome: Term Details for "Nkx-2.5 complex" (GO:1990664)

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Term Information

Accession: GO:1990664
Name: Nkx-2.5 complex
Ontology: cellular_component
Synonyms: NKX.2-5 homodimer complex, NKX2.5 complex, NKX2E homodimer complex, Nkx-2.5 homodimer complex
Alternate IDs: None
Definition: A transcription factor complex formed by two or more subunits of Nkx-2.5. Nkx-2.5 is an evolutionary conserved transcription factor important for the specification and differentiation of cardiomyocytes during heart development. It is also required for spleen development. It binds DNA either as a monomer, or a homodimer, or a heterodimer complex to activate or inhibit expression of genes. Source: PMID:22849347, GOC:ame
Comment: An example of this is Nkx-2.5 in human (UniProt symbol P52952) in PMID:22849347 (inferred from direct assay).
History: See term history for GO:1990664 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to Nkx-2.5 complex.; Link to all direct and indirect annotations to Nkx-2.5 complex.; Link to all direct and indirect annotations download (limited to first 10,000) for Nkx-2.5 complex.
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